Ortho Lawn Weed Killers and Home Defense Insect Killers for Your Yard

From Ant & Roach Killers to Nutsedge & Crabgrass Killers, Ortho builds one-application solutions that actually finish the job.

Shop the collection
Ortho lawn weed killers

Featured Ortho Products

What Our Customers Say

★★★★★

Denise Farrow, weekend gardener in a townhouse complex

I sprayed the WeedClear on a patch of creeping charlie that had been driving me crazy for two summers. It was yellow within a day and gone within the week, and my fescue never even flinched.

★★★★★

Marcus Odom, amateur woodworker with a garage full of spiders

Bought the Home Defense sprayer mostly for the garage and around the foundation. The wand makes it stupid easy to spray without bending over, and I haven't seen a roach since. Worth it.

★★★★★

Priya Nathan, part-time dog walker

Used the concentrate on clover taking over a rental property's front lawn. Diluted it per the label, hit it once, and the clover was toast in about a week while the grass stayed green. Simple stuff, does what it says.

★★★★★

Gary Holbrook, retired mail carrier, backyard tinkerer

Rainproof in an hour sounded like marketing until a storm rolled in thirty minutes after I sprayed the dandelions. They still died. No regrowth so far, and that's really all I wanted.

About Ortho

A garage sprayer with a dead battery is how most weed problems get worse, not better. Ortho's approach starts from that frustration: a battery-powered Comfort Wand that delivers continuous spray so nobody has to pump a handle fifty times just to treat a patio. The line grew out of practical complaints from DIY homeowners who wanted lawn weed killers that worked on Bermudagrass and Kentucky Bluegrass without wrecking the lawn, and insect sprays that didn't leave stains or fumes behind in a kitchen. That's the throughline across the catalog. A 1.33 gallon ready-to-use container for perimeter and indoor work. A 32 oz concentrate for spot treatments. Formulas rainproof in one to six hours, because nobody controls the weather on treatment day. Nothing here promises magic. It promises coverage numbers, timeframes, and results you can check by walking outside a week later. That's the standard the brand holds itself to, and it's the reason the same names keep showing up on porches and in garages every spring.

Why Choose Ortho?

What sets Ortho apart is the specificity. A 32 fl. oz. concentrate that treats up to 5,000 sq. ft. isn't a vague promise, it's a number you can measure your yard against. The Home Defense line backs up its Ant & Roach Killers and Wasp, Hornet & Flying Insect Killers claims with actual protection windows, up to 12 months indoors on non-porous surfaces, so you're not respraying every month. Weed & Grass Killers and Nutsedge & Crabgrass Killers go after roots, not just leaves, which is why regrowth stays gone for a season instead of two weeks. And the Comfort Wand means you're not hunched over a tank sprayer for an hour just to treat a driveway crack or a fence line.

Frequently Asked Questions

Does Ortho lawn weed killer actually work?

Yes, when applied as directed. Ortho WeedClear kills over 200 listed broadleaf and grass weeds, including dandelion, clover, and crabgrass, down to the root, and Weed B Gon handles chickweed, clover, and oxalis. Both are formulated to get results with a single application rather than repeated treatments.

Which Ortho weed killer should I choose for my lawn?

It depends on the weeds you have and your lawn type. WeedClear is broader-spectrum, covering over 200 weeds and safe on Bermudagrass, Buffalograss, Fescues, Kentucky Bluegrass, Ryegrass, and Zoysiagrass. Weed B Gon targets chickweed, clover, oxalis, creeping Charlie, ground ivy, and wild violet specifically. Check the label against the weeds in your yard before deciding.

Should I mow before spraying Ortho weed killer?

The product details do not specify a mowing requirement, but weeds generally absorb herbicide better when they have enough leaf surface exposed. Follow the label directions on your specific bottle for timing, since application steps vary between WeedClear and Weed B Gon.

How long does it take for Ortho weed killer to work?

WeedClear is fast-acting and rainproof within 1 hour, with visible results from a single application. Weed B Gon is rainproof in 6 hours. Neither product lists an exact number of days to full results, so expect the weeds to die back to the root over the following days rather than instantly.

How long before rain can I expect after applying Ortho?

WeedClear becomes rainproof in 1 hour, and Weed B Gon is rainproof in 6 hours, meaning rain after that window shouldn't wash away the treatment. Try to apply when no rain is forecast during that initial period so the formula has time to absorb into the weeds.

Can I spray Ortho weed killer on wet grass?

The product details don't give a direct answer on wet grass application, so it's best to follow the specific label instructions on your bottle. Since these formulas work by absorption into the weed, applying to dry foliage is generally the safer approach when the label doesn't state otherwise.

Is it possible to use too much Ortho weed killer on my lawn?

Always dilute and apply according to the label directions; WeedClear concentrate is meant to be diluted for use with a tank sprayer or the Ortho Dial N Spray, and the ready-to-use versions are pre-measured. Using more than directed won't harm the lawn if you follow the coverage guidance, such as the 5,000 sq. ft. or 6,400 sq. ft. treatment areas listed.

Does Ortho Home Defense Insect Killer actually work on ants, roaches, and spiders?

Yes. It kills tough home-invading insects including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, and silverfish, and creates a bug barrier offering up to 12 months of protection against ants, roaches, and spiders when applied indoors on non-porous surfaces.

Can I stay in my house after spraying Ortho Home Defense?

The product is designed for use in kitchens, bathrooms, and around doors and windows, suggesting it's meant for occupied homes. The details don't specify a mask requirement or re-entry time, so check the label on your container for exact safety directions before and after application.

How do I use Ortho Home Defense indoors and around the perimeter?

The 1.33 gal. ready-to-use container comes with a battery-powered Comfort Wand sprayer for continuous, easy spraying. Use it indoors around kitchens, bathrooms, doors, and windows, and outdoors along foundations, patios, decks, and garages, applying either as a preventative measure or after you notice insect activity.